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Die Naturheilkunde 01/2025 (Februar-Ausgabe)


Seite 39: Gehirnleistung, kognitive Störungen, Demenz – Welche Rolle spielen Ernährung und Biofaktoren?

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[7] Lee KH et al.: Neuroprotective Effect of Antioxidants in the Brain. Int J Mol Sci. 2020 Sep 28; 21(19): 7152

[8]www.gf-biofaktoren.de/wissenswertes-ueber-biofaktoren/steckbriefe/

[9] Kennedy DO et al.: Polyphenols and the Human Brain: Plant "Secondary Metabolite” Ecologic Roles and Endogenous Signaling Functions Drive Benefits. Advances in Nutrition. Volume 5, Issue 5, September 2014, Pages 515-533

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[15] Gibson GE et al.: Benfotiamine and cognitive decline in Alzheimer's disease: Results of a randomized placebo-controlled phase IIa clinical trial. J Alzheimers Dis 2020; 78(3): 989-1010

[16] Chen H et al.: Associations between Alzheimer's disease and blood homocysteine, vitamin B12and folate: a case-control study. Curr Alzheimer Res 2015; 12(1): 88-94

[17] Jatoi S. et al.: Low vitamin B12 levels: An underestimated cause of minimal cognitive impairment and dementia. Cureus 2020 Feb 13; 12(2): e6976

[18] Schreeb KH et al.: Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate. Eur J Clin Pharmacol 1997; 52(4): 319-320

[19] Loew D: Pharmacokinetics of thiamine derivatives especially of benfotiamine. Inter J of Clin Pharm and Ther 1996; 34(2): 47-50

[20] Raj V et al.: Therapeutic potential of benfotiamine and its molecular targets. Eur Rev Med Pharmacol Sci 2018; 22: 3261-3273

[21] Pan X et al.: Powerful beneficial effects of benfotiamine on cognitive impairment and ?-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice. Brain 2010; 133(5): 1342-1351

[22] Gibson GE et al.: Benfotiamine and cognitive decline in Alzheimer's disease: Results of a randomized placebo-controlled phase IIa clinical trial. J Alzheimers Dis 2020; 78(3): 989-1010

[23] Enderami A et al.: The effects and potential mechanisms of folic acid on cognitive function: a comprehensive review. Neurol Sci 2018 Oct; 39(10): 1667-1675

[24] Puga AM et al.: Effects of Supplementation with Folic Acid and Its Combinations with Other Nutrients on Cognitive Impairment and Alzheimer’s Disease: A Narrative Review. Nutrients 2021 Aug 26; 13(9): 2966

[25] Chen H et al.: Effects of Folic Acid and Vitamin B12 Supplementation on Cognitive Impairment and Inflammation in Patients with Alzheimer's Disease: A Randomized, Single-Blinded, Placebo-Controlled Trial. J Prev Alzheimers Dis 2021; 8(3): 249-256

[26]www.gesundheitsamt.bremen.de/erwachsene/ernaehrung-im-alter/ernaehrung-und-demenz-12948

[27] Köbe T et al.: Vitamin B12 concentration, memory performance and hippocampal structure in patients with mild cognitive impairment. Am J Clin Nutr 2016 Apr; 103(4): 1045-1054

[28] Chen H et al.: Associations between Alzheimer's disease and blood homocysteine, vitamin B12and folate: a case-control study. Curr Alzheimer Res 2015; 12(1): 88-94

[29] Djukic M et al.: Frequency of dementia syndromes with a potentially treatable cause in geriatric in-patients: analysis of a 1-year interval. Eur Arch Psychiatry Clin Neurosci 2015 Aug; 265(5): 429-438

[30] Jatoi S. et al.: Low vitamin B12 levels: An underestimated cause of minimal cognitive impairment and dementia. Cureus 2020 Feb 13; 12(2): e6976

[31] Moore E et al.: Cognitive impairment and vitamin B12: a review. Psychogeriatr 2012 Apr; 24(4): 541-556

[32] Lauer AA et al.: Mechanistic link between vitamin B12 and Alzheimer's Disease. Biomolecules 2022 Jan 14; 12(1): 129

[33] Cho HS et al: Suboptimal baseline serum vitamin B12 is associated with cognitive decline in people with Alzheimer’s disease undergoing cholinesterase inhibitor treatment. Front Neurol 2018 May 9; 9: 325

[34]www.dge.de/wissenschaft/referenzwerte/vitamin-b12/

[35] Andrès et al.: Systematic review and pragmatic clinical approach to oral and nasal vitamin B12 (Cobalamin) treatment in patients with vitamin B12 deficiency related to gastrointestinal disorders. J Clin Med 2018; 7: 304